Arsenical Pigmentation and Hyperkeratosis

Arsenical polyneuropathy due to caustic arsenical paste.

Arsenical Neuritis

use of impure acids containing arsenic used for the manufacture of glucose and " invert" sugar. The number of cases amounted to over 6,000 and of deaths to at least 70. Many deaths returned as due to, "alcoholic neuritis" "alcoholism," "locomotor ataxy," &c., were probably caused by arsenical poisoning. Since the exposure of the cause of the outbreak and discontinuance of the use of impure acid...

Hyperkeratosis lenticularis perstans.

Flegel's disease, also known as hyperkeratosis lenticularis perstans, is a rare skin disease characterized by small reddish-brown asymptomatic hyperkeratotic papules usually located on the lower extremities. The histopathological features are hyperorthokeratosis, epidermal atrophy and band-like inflammatory infiltrate in the superficial dermis. Treatment is generally ineffective. We report a ca...

Epidermolytic hyperkeratosis with rickets.

A 6-year-old child presented with generalized hyperkeratosis, most marked over the flexures; windswept deformity of the legs; and limping since 3 years. On the basis of the clinical, histopathologic and biochemical findings, he was diagnosed as a case of epidermolytic hyperkeratosis with rickets. He was treated with parenteral vitamin D3 and calcium supplements orally. Nutritional rickets has b...

Epidermolytic Hyperkeratosis report

A 20 year old boy presented to the dermatology department for treatment of a congenital icthyosis with a history of generalized erythroderma and trauma related blistering since birth. At the time of presentation he was noted to have red hyperkeratotic plaq corrugated over the joint flexures, elbows, knees after birth erythema and blistering improved but patient developed hyperkeratotic scaling ...